I am only trading TBT electronically using Tradestation at this time. The commission seems to be the same as any other ETF or stock, which is $1 for a block of 100. Although the daily volume is not high, the market is liquid enough to enter and exit within seconds.
I try to buy near the bottom of the TR and sell near the top of the TRs that evolve - not necessarily in that order. Since this is likely accumulation in TBT (and distribution in interest products), I try to buy more at the bottom of the TR and hold some at the top of the TR, when it looks like a jump is possible.
Peter